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Article

The TRP calcium channel and retinal degeneration.

Advances in experimental medicine and biology - 1 Jan 2002

Minke Baruch

Abstract excerpt

The Drosophila light activated channel TRP is the founding member of a large and diverse family of channel proteins that is conserved throughout evolution. These channels are Ca2+ permeable and have been implicated as important component of cellular Ca2+ homeostasis in neuronal and non-neuronal cells. The power of the molecular genetics of Drosophila has yielded several mutants in which constitutive activity of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12596945
DOI: 10.1007/978-1-4615-0121-3_34

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The TRP calcium channel and retinal degeneration.PMID 12596945Read ↗

Exploring Excitotoxicity and Regulation of a Constitutively Active TRP Ca2+ Channel in Drosophila.Semantic proximity Read ↗

The roles of trp and calcium in regulating photoreceptor function in Drosophila.Semantic proximity Read ↗

The TRP channel and phospholipase C-mediated signaling.Semantic proximity Read ↗

Novel mechanism of massive photoreceptor degeneration caused by mutations in the trp gene of Drosophila.Semantic proximity Read ↗

Photoreceptor degeneration and Ca2+ influx through light-activated channels of Drosophila.Semantic proximity Read ↗

The Drosophila light-activated conductance is composed of the two channels TRP and TRPL.Semantic proximity Read ↗

Activation of the Drosophila TRP and TRPL channels requires both Ca2+ and protein dephosphorylation.Semantic proximity Read ↗

In vivo identification and manipulation of the Ca2+ selectivity filter in the Drosophila transient receptor potential channel.Semantic proximity Read ↗

TRP channels: molecular diversity and physiological function.Semantic proximity Read ↗

Phosphoinositide-mediated phototransduction in Drosophila photoreceptors: the role of Ca2+ and trp.Semantic proximity Read ↗

New light on TRP and TRPL.Semantic proximity Read ↗

The trp gene is essential for a light-activated Ca2+ channel in Drosophila photoreceptors.Semantic proximity Read ↗

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