Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Origin of antibacterial stasis by polymyxin B in Escherichia coli.

Biochimica et biophysica acta - 15 Jan 2000

Liechty A, Chen J, Jain M K

Abstract excerpt

We show that blockage of hyperosmotic shock induced plasmolysis by polymyxin B (PxB) is related to its selective antimicrobial action against Gram-negative organisms. The rapid wrinkling of the cytoplasmic membrane induced by the hyperosmotic shrinkage of cytoplasmic volume due to the water efflux is monitored as an increase in the 90 degrees light scattering. The rapid scattering response is complete within 1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Membrane
Share to Escherichia coli Proteins
Share to Light

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Osmotic Pressure

Share to Periplasmic Binding Proteins

Share to Phospholipids

Share to Polymyxin B

Share to Scattering, Radiation

Source

Identifiers

PMID: 10631294
DOI: 10.1016/s0005-2736(99)00178-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Origin of antibacterial stasis by polymyxin B in Escherichia coli.PMID 10631294Read ↗

The rate of osmotic downshock determines the survival probability of bacterial mechanosensitive channel mutants.Semantic proximity Read ↗

A Delicate Connection: c-di-AMP Affects Cell Integrity by Controlling Osmolyte Transport.Semantic proximity Read ↗

Cell-Biological Studies of Osmotic Shock Response in Streptomyces spp.Semantic proximity Read ↗

Mutations in a bacterial mechanosensitive channel change the cellular response to osmotic stress.Semantic proximity Read ↗

MscL of Bacillus subtilis prevents selective release of cytoplasmic proteins in a hypotonic environment.Semantic proximity Read ↗

Pseudomonas aeruginosa-Induced Bleb-Niche Formation in Epithelial Cells Is Independent of Actinomyosin Contraction and Enhanced by Loss of Cystic Fibrosis Transmembrane-Conductance Regulator Osmoregulatory FunctionSemantic proximity Read ↗

Osmotic stress mechanically perturbs chemoreceptors in Escherichia coli.Semantic proximity Read ↗

Characterization of three novel mechanosensitive channel activities in Escherichia coli.Semantic proximity Read ↗

Molecular and physiological analysis of the role of osmolyte transporters BetL, Gbu, and OpuC in growth of Listeria monocytogenes at low temperatures.Semantic proximity Read ↗

Phage shock proteins B and C prevent lethal cytoplasmic membrane permeability in Yersinia enterocolitica.Semantic proximity Read ↗

From penicillin-binding proteins to the lysis and death of bacteria: a 1979 view.Semantic proximity Read ↗

Protection of Escherichia coli cells against extreme turgor by activation of MscS and MscL mechanosensitive channels: identification of genes required for MscS activity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.