Article
Linkage disequilibrium and allele-frequency distributions for 114 single-nucleotide polymorphisms in five populations.
American journal of human genetics - 1 Jan 2000
Goddard K A, Hopkins P J, Hall J M, Witte J S
Abstract excerpt
Single-nucleotide polymorphisms (SNPs) may be extremely important for deciphering the impact of genetic variation on complex human diseases. The ultimate value of SNPs for linkage and association mapping studies depends in part on the distribution of SNP allele frequencies and intermarker linkage disequilibrium (LD) across populations. Limited information is available about these distributions on a genomewide...
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