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A novel phenotype for Lardon dwarfism in miniature Bos indicus cattle suggests that the expression of growth hormone receptor 1A in liver is required for normal growth.

Domestic animal endocrinology - 1 Nov 1999

Liu J, Boyd C K, Kobayashi Y, Chase C C, Hammond A C, Olson T A, Elsasser T H, Lucy M C

Abstract excerpt

Mutations within the growth hormone receptor (GHR) gene that lead to an inactivated or truncated GHR protein cause abnormal growth and small adult size in a variety of species (Laron dwarfism). We studied a line of miniature Bos indicus cattle that have phenotypic (small mature size) and endocrine (increased blood growth hormone and decreased blood insulin-like growth factor-I concentrations) similarities to...

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Source

Identifiers

PMID: 10628432
DOI: 10.1016/s0739-7240(99)00051-x

Genes

GHR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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