Article
Immunostimulatory virotherapy using recombinant Sendai virus as a new cancer therapeutic regimen.
Frontiers in bioscience : a journal and virtual library - 1 Jan 2008
Yonemitsu Yoshikazu, Ueda Yasuji, Kinoh Hiroaki, Hasegawa Mamoru
Abstract excerpt
The utility of recombinant Sendai virus (rSeV) has been considerably examined over the last decade as a potent gene transfer candidate in a cytoplasmic gene expression system. Such risks as excessive immune responses associated with this virus administration in vivo however have limited its applicability in clinical settings as is the case with other viral vectors including adenoviruses. In consequence of...
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