Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Long-chain fatty acid-induced changes in gene expression in neonatal cardiac myocytes.

Journal of lipid research - 1 Jan 2000

van der Lee K A, Vork M M, De Vries J E, Willemsen P H, Glatz J F, Reneman R S, Van der Vusse G J, Van Bilsen M

Abstract excerpt

Long-chain fatty acids are the most important substrates for the heart. In addition, they have been shown to affect signalling pathways and gene expression. To explore the effects of long-chain fatty acids on cardiac gene expression, neonatal rat ventricular myocytes were cultured for 48 h with either glucose (10 mm), fatty acids (palmitic and oleic acid, 0.25 mm each), or a combination of both as exogenous...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Newborn
Share to Cells, Cultured

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fatty Acids

Share to Gene Expression Regulation

Share to Heart Ventricles

Share to Ligands

Share to Receptors, Cytoplasmic and Nuclear

Source

Identifiers

PMID: 10627500

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Long-chain fatty acid-induced changes in gene expression in neonatal cardiac myocytes.PMID 10627500Read ↗

Fatty Acids and Their Roles in Cardiac Physiology and Pathology: Mechanistic and Interventional StudiesSemantic proximity Read ↗

Fatty Acids and Their Roles in Cardiac Physiology and Pathology: Mechanistic and Interventional StudiesSemantic proximity Read ↗

Transcriptional regulation profiling reveals PPARA-mediated fatty acid oxidation as a novel therapeutic target in phospholamban R14del cardiomyopathySemantic proximity Read ↗

Maternal obesity causes fetal cardiac hypertrophy and alters adult offspring myocardial metabolism in miceSemantic proximity Read ↗

The Pivotal Role of miRNA-21 in Myocardial Metabolic Flexibility in Response to Short- and Long-term High Glucose Treatment: Evidence in Human Cardiomyocyte Cell LineSemantic proximity Read ↗

Very-long-chain acyl-coenzyme a dehydrogenase deficiency in mice.Semantic proximity Read ↗

Maternal High Fat Diet and Diabetes Disrupts Transcriptomic Pathways That Regulate Cardiac Metabolism and Cell Fate in Newborn Rat HeartsSemantic proximity Read ↗

Energy metabolic phenotype of the cardiomyocyte during development, differentiation, and postnatal maturation.Semantic proximity Read ↗

Energy Metabolism on Mitochondrial Maturation and Its Effects on Cardiomyocyte Cell FateSemantic proximity Read ↗

Fatty acid synthase modulates homeostatic responses to myocardial stress.Semantic proximity Read ↗

Prenatal Exposure to a Maternal High-Fat Diet Affects Histone Modification of Cardiometabolic Genes in Newborn Rats.Semantic proximity Read ↗

Human fetal ventricular cardiomyocyte, RL-14 cell line, is a promising model to study drug metabolizing enzymes and their associated arachidonic acid metabolitesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.