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Article

Essentiality of intron control in the induction of c-fos by glucose and glucoincretin peptides in INS-1 beta-cells.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jan 2000

Susini S, Van Haasteren G, Li S, Prentki M, Schlegel W

Abstract excerpt

Glucose controls long-term processes in the pancreatic beta-cell such as metabolic enzymes gene expression, cell growth, and apoptosis. Such control is likely mediated via the expression of immediate-early response genes since several of these genes including c-fos are strongly induced by glucose in the beta-cell line INS-1, provided costimulation with cAMP-raising glucoincretin hormones. This study addresses the...

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PMID: 10627287

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INS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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