Screening unlabeled DNA targets with randomly ordered fiber-optic gene arrays.

Abstract excerpt

We have developed a randomly ordered fiber-optic gene array for rapid, parallel detection of unlabeled DNA targets with surface immobilized molecular beacons (MB) that undergo a conformational change accompanied by a fluorescence change in the presence of a complementary DNA target. Microarrays are prepared by randomly distributing MB-functionalized 3-microm diameter microspheres in an array of wells etched in a...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Biotin
• Share to Cystic Fibrosis Transmembrane Conductance Regulator
• Share to Fluorescent Dyes