Article
Cholesteryl ester transfer protein gene polymorphisms are associated with carotid atherosclerosis in men.
European journal of clinical investigation - 1 Jan 2000
Kakko S, Tamminen M, Päivänsalo M, Kauma H, Rantala A O, Lilja M, Reunanen A, Kesäniemi Y A, Savolainen M J
Abstract excerpt
BACKGROUND: The cholesteryl ester transfer protein (CETP) is involved in the reverse cholesterol transport and is therefore a candidate gene for atherosclerosis. DESIGN: The prevalences of the I405V and the R451Q polymorphisms were studied in a population sample of 515 men and women. Genotypes were determined by PCR and carotid atherosclerosis by ultrasonography as the mean intima-media thickness (IMT) of the...
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