Article
Pharmacogenetic study of cholesteryl ester transfer protein gene and simvastatin treatment in hypercholesterolaemic subjects.
Expert opinion on pharmacotherapy - 1 Oct 2007
Anagnostopoulou Katherine, Kolovou Genovefa, Kostakou Peggy, Mihas Constantinos, Mikhailidis Dimitri, Cokkinos Dennis V
Abstract excerpt
OBJECTIVE: To examine the effect of the I405V and TaqIB polymorphisms of cholesteryl ester transfer protein (CETP) on the lipid response after simvastatin treatment in 180 hypercholesterolaemic patients. METHODS: Hypercholesterolaemic patients (n = 180) attending the lipid clinic at the Onassis Cardiac Surgery Center were genotyped and their response to simvastatin was evaluated. RESULTS: Sequence variations in...
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