Article
Lambert-Eaton myasthenic syndrome.
Postgraduate medical journal - 1 Sept 1999
Seneviratne U, de Silva R
Abstract excerpt
The Lambert-Eaton myasthenic syndrome is a neuromuscular disorder characterised by defective neurotransmitter release at autonomic neurones and presynaptic terminals of the neuromuscular junction. It is caused by an IgG autoantibody formed against especially the P/Q type of voltage-gated calcium channels (VGCC) which is an essential component of the mechanism of neurotransmitter release. Many patients have an...
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