Article
B cells lacking RP105, a novel B cell antigen, in systemic lupus erythematosus.
Arthritis and rheumatism - 1 Dec 1999
Koarada S, Tada Y, Ushiyama O, Morito F, Suzuki N, Ohta A, Miyake K, Kimoto M, Nagasawa K
Abstract excerpt
OBJECTIVE: RP105 is a leucine-rich repeat (LRR) protein found on all mature mouse B cells. Its function is poorly defined, although it has been suggested that RP105 activates B cells to make them resistant to apoptosis. The human homolog of RP105 has been reported, but knowledge of its function is limited. We explored the expression and the function of the human homolog of murine RP105 on B cells in patients with...
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