Article
Cystic Fibrosis Transmembrane Conductance Regulator–Dependent Regulation of Epithelial Inducible Nitric Oxide Synthase Expression
1 Jan 2000
Abstract excerpt
Recent evidence has shown that the inducible form of nitric oxide (NO) synthase (NOS2) has reduced expression in airway epithelia of patients with cystic fibrosis (CF) despite the presence of chronic inflammation. The goal of this paper is to determine whether NOS2 expression is regulated by the presence of functional CF transmembrane conductance regulator (CFTR). Using a human trachea epithelial cell line in...
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