Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reduction of neuronal and inducible nitric oxide synthase gene expression in patients with cystic fibrosis.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery - 1 Apr 2002

Dötsch Jörg, Puls Jan, Klimek Thorsten, Rascher Wolfgang

Abstract excerpt

As a consequence of diminished nitric oxide synthase (NOS) protein concentration, the airway concentration of nitric oxide (NO) is reduced in patients with cystic fibrosis (CF). This appears to lead to a reduced elimination of such microorganisms as Pseudomonas aeruginosa. The objective of this s...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cystic Fibrosis
Share to Cystic Fibrosis Transmembrane Conductance Regulator

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Nasal Polyps

Share to Nasopharynx

Share to Nitric Oxide Synthase

Share to Nitric Oxide Synthase Type I

Share to Nitric Oxide Synthase Type II

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 12064512
DOI: 10.1007/s00405-001-0436-8

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12064512-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reduction of neuronal and inducible nitric oxide synthase gene expression in patients with cystic fibrosis.PMID 12064512Read ↗

Nasal and exhaled nitric oxide is reduced in adult patients with cystic fibrosis and does not correlate with cystic fibrosis genotype.Semantic proximity Read ↗

Airway nitric oxide levels in cystic fibrosis patients are related to a polymorphism in the neuronal nitric oxide synthase gene.Semantic proximity Read ↗

Cystic Fibrosis Transmembrane Conductance Regulator–Dependent Regulation of Epithelial Inducible Nitric Oxide Synthase ExpressionSemantic proximity Read ↗

Nasal nitric oxide levels in cystic fibrosis patients are associated with a neuronal NO synthase (NOS1) gene polymorphism.Semantic proximity Read ↗

Endogenous nitric oxide production in airways of patients with cystic fibrosisSemantic proximity Read ↗

Signal transduction and oxidative processes in sinonasal polyposis.Semantic proximity Read ↗

Nitric oxide synthase polymorphisms, gene expression and lung function in chronic obstructive pulmonary disease.Semantic proximity Read ↗

EDNRA variants associate with smooth muscle mRNA levels, cell proliferation rates, and cystic fibrosis pulmonary disease severity.Semantic proximity Read ↗

Airway nitric oxide in patients with cystic fibrosis is associated with pancreatic function, Pseudomonas infection, and polyunsaturated fatty acids.Semantic proximity Read ↗

Reduced exhaled NO is related to impaired nasal potential difference in patients with cystic fibrosis.Semantic proximity Read ↗

Influence of cystic fibrosis transmembrane conductance regulator on gene expression in response to Pseudomonas aeruginosa infection of human bronchial epithelial cells.Semantic proximity Read ↗

Role of nitric oxide in P. aeruginosa keratitis caused by distinct bacterial phenotypes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.