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Article

Reduction of neuronal and inducible nitric oxide synthase gene expression in patients with cystic fibrosis.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery - 1 Apr 2002

Dötsch Jörg, Puls Jan, Klimek Thorsten, Rascher Wolfgang

Abstract excerpt

As a consequence of diminished nitric oxide synthase (NOS) protein concentration, the airway concentration of nitric oxide (NO) is reduced in patients with cystic fibrosis (CF). This appears to lead to a reduced elimination of such microorganisms as Pseudomonas aeruginosa. The objective of this study was to analyze whether inducible (iNOS), endothelial (eNOS) and neuronal (bNOS) NOS are reduced at mRNA level and...

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PMID: 12064512
DOI: 10.1007/s00405-001-0436-8

Genes

CFTR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Reduction of neuronal and inducible nitric oxide synthase gene expression in patients with cystic fibrosis.PMID 12064512Read ↗

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