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Article

Adaptation and conservation of physiological systems in the evolution of human hypoxia tolerance.

Comparative biochemistry and physiology. Part A, Molecular & integrative physiology - 1 Sept 1999

Hochachka P W, Rupert J L, Monge C

Abstract excerpt

Analysis of human responses to hypobaric hypoxia in different lineages (lowlanders, Andean natives, Himalayan natives, and East Africans) indicates 'conservative' and 'adaptable' physiological characters involved in human responses to hypoxia. Conservative characters, derived by common descent, dominate and indeed define human physiology, but in five hypoxia response systems analyzed, we also found evidence for...

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PMID: 10605062
DOI: 10.1016/s1095-6433(99)00079-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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