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Article

High-Altitude Adaptation: Mechanistic Insights from Integrated Genomics and Physiology.

Molecular biology and evolution - 25 Jun 2021

Storz Jay F

Abstract excerpt

Population genomic analyses of high-altitude humans and other vertebrates have identified numerous candidate genes for hypoxia adaptation, and the physiological pathways implicated by such analyses suggest testable hypotheses about underlying mechanisms. Studies of highland natives that integrate genomic data with experimental measures of physiological performance capacities and subordinate traits are revealing...

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Share to Basic Helix-Loop-Helix Transcription Factors
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Hypoxia

Share to Hypoxia-Inducible Factor-Proline Dioxygenases

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Source

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Identifiers

PMID: 33751123
DOI: 10.1093/molbev/msab064
PMCID: PMC8233491

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