Article
Differential expression of estrogen receptor-beta (ER beta) in human pituitary tumors: functional interactions with ER alpha and a tumor-specific splice variant.
The Journal of clinical endocrinology and metabolism - 1 Sept 1998
Chaidarun S S, Swearingen B, Alexander J M
Abstract excerpt
The mitogenic and regulatory effects of estrogen (E2) in adenohypophysial cells are known to be mediated through the nuclear estrogen receptor (ER alpha). Expression of ER alpha and several of its messenger ribonucleic acid (RNA) alternate splice variants has been shown to be restricted to prolac...
Topics
- Adenoma
- Adolescent
- Adult
- Aged
- Alternative Splicing
- Cloning, Molecular
- Estradiol
- Gene Expression
- Genetic Variation
- Humans
- Middle Aged
- Pituitary Neoplasms
- Polymerase Chain Reaction
- Prolactinoma
- RNA, Messenger
- RNA-Directed DNA Polymerase
- Receptors, Estrogen
- Regulatory Sequences, Nucleic Acid