Article
Tumor-specific expression of alternatively spliced estrogen receptor messenger ribonucleic acid variants in human pituitary adenomas.
The Journal of clinical endocrinology and metabolism - 1 Apr 1997
Chaidarun S S, Klibanski A, Alexander J M
Abstract excerpt
The well documented mitogenic and hormone regulatory effects of estrogen (E2) on pituitary cells are mediated via its nuclear receptor (ER), a cellular homolog of v-erbA oncogene. ER isoforms generated by alternative exon splicing, termed ER variants delta 2ER to delta 7ER, have been identified i...
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