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Article

Stimulation of c-Src by prolactin is independent of Jak2.

The Biochemical journal - 1 Jan 2000

Fresno Vara J A, Carretero M V, Gerónimo H, Ballmer-Hofer K, Martín-Pérez J

Abstract excerpt

Interaction of prolactin (PRL) with its receptor (PRLR) leads to activation of Jak and Src family tyrosine kinases. The PRL/growth hormone/cytokine receptor family conserves a proline-rich sequence in the cytoplasmic juxtamembrane region (Box 1) required for association and subsequent activation of Jaks. In the present work, we studied the mechanisms underlying c-Src kinase activation by PRL and the role that...

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Source

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Identifiers

PMID: 10600634
DOI: 10.1042/0264-6021:3450017
PMCID: PMC1220725

Genes

PRL
PRLR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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