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Article

Threonine 391 phosphorylation of the human prolactin receptor mediates a novel interaction with 14-3-3 proteins.

The Journal of biological chemistry - 29 Aug 2003

Olayioye Monilola A, Guthridge Mark A, Stomski Frank C, Lopez Angel F, Visvader Jane E, Lindeman Geoffrey J

Abstract excerpt

The prolactin receptor (PrlR) is a member of the cytokine receptor superfamily that lacks an intrinsic kinase domain and relies on the cytoplasmic Jak tyrosine kinases to transduce signals. Prolactin-induced Jak2 activation and consequent tyrosine phosphorylation of the receptor and downstream signaling molecules have been studied, but phosphorylation of the PrlR on serine or threonine residues has not been...

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Identifiers

PMID: 12819209
DOI: 10.1074/jbc.M302910200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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