Article
A prolactin-dependent immune cell line (Nb2) expresses a mutant form of prolactin receptor.
The Journal of biological chemistry - 25 Oct 1991
Ali S, Pellegrini I, Kelly P A
Abstract excerpt
The Nb2 cell line is a pre-T rat lymphoma that is dependent on prolactin (PRL) for mitogenesis. Two forms of PRL receptor (PRL-R), which differ in the length of their cytoplasmic domains have been identified in different tissues and species. In the present study we have cloned the cDNA and charac...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Blotting, Northern
- Blotting, Western
- Cell Line
- DNA
- Molecular Sequence Data
- Mutation
- Nucleic Acid Hybridization
- Polymerase Chain Reaction
- Prolactin
- RNA
- Rats
- Receptors, Prolactin