Article
Sib-pair linkage analyses of alcoholism: dichotomous and quantitative measures.
Genetic epidemiology - 1 Jan 1999
Korczak J F, Bergen A W, Goldstein A M, Weissbecker K A
Abstract excerpt
We hypothesized that a quantitative alcoholism trait would have greater power than the Collaborative Study on the Genetics of Alcoholism (COGA) dichotomous alcoholism traits, ALDX1 and ALDX2, to detect putative alcoholism loci. To test this, we performed nonparametric sib-pair linkage analysis to screen 285 polymorphic autosomal markers for evidence of linkage to ALDX1, ALDX2, and a quantitative trait, QUANT,...
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