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Article

Comparison of genotype- and haplotype-based approaches for fine-mapping of alcohol dependence using COGA data.

BMC genetics - 30 Dec 2005

Pinnaduwage Dushanthi, Briollais Laurent

Abstract excerpt

It is generally assumed that the detection of disease susceptibility genes via fine-mapping association study is facilitated by consideration of marker haplotypes. In this study, we compared the performance of genotype-based and haplotype-based association studies using the Collaborative Study of Genetics of Alcoholism dataset, on several chromosomal regions showing evidence for linkage with ALDX1. After...

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Identifiers

PMID: 16451678
DOI: 10.1186/1471-2156-6-S1-S65
PMCID: PMC1866717

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