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Article

Association of the dopamine transporter gene (DAT1) with poor methylphenidate response.

Journal of the American Academy of Child and Adolescent Psychiatry - 1 Dec 1999

Winsberg B G, Comings D E

Abstract excerpt

OBJECTIVE: This study attempted to relate the alleles of the D2 (DRD2), D4 (DRD4), and dopamine transporter (DAT1) genes to the behavioral outcome of methylphenidate therapy. METHOD: African-American children with attention-deficit hyperactivity disorder were treated with methylphenidate in doses...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10596245
DOI: 10.1097/00004583-199912000-00006

Genes

DRD2
DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10596245-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Association of the dopamine transporter gene (DAT1) with poor methylphenidate response.PMID 10596245Read ↗

Dopamine transporter genotype and methylphenidate dose response in children with ADHD.Semantic proximity Read ↗

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Association of dopamine, serotonin, and nicotinic gene polymorphisms with methylphenidate response in ADHD.Semantic proximity Read ↗

Association of the 480 bp DAT1 allele with methylphenidate response in a sample of Irish children with ADHDSemantic proximity Read ↗

Absence of association with DAT1 polymorphism and response to methylphenidate in a sample of adults with ADHD.Semantic proximity Read ↗

A candidate gene analysis of methylphenidate response in attention-deficit/hyperactivity disorder.Semantic proximity Read ↗

Response to methylphenidate is not influenced by DAT1 polymorphisms in a sample of Brazilian adult patients with ADHD.Semantic proximity Read ↗

Response to methylphenidate in adults with ADHD is associated with a polymorphism in SLC6A3 (DAT1).Semantic proximity Read ↗

Association of norepinephrine transporter gene with methylphenidate response.Semantic proximity Read ↗

Pharmacogenetic predictors of methylphenidate dose-response in attention-deficit/hyperactivity disorder.Semantic proximity Read ↗

A candidate gene investigation of methylphenidate response in adult attention-deficit/hyperactivity disorder patients: results from a naturalistic study.Semantic proximity Read ↗

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