Article
The VITA project: prothrombin G20210A mutation and venous thromboembolism in the general population.
Thrombosis and haemostasis - 1 Nov 1999
Tosetto A, Missiaglia E, Frezzato M, Rodeghiero F
Abstract excerpt
Recently a new identified genetic variant in the 3'-untranslated region of the prothrombin gene (G20210A allele) associated with increased plasma prothrombin levels has been linked to an increased risk of venous thromboembolism (VTE). Most of our knowledge on the G20210A allele as a risk factor for VTE derives from a population-based case-control study and from studies on selected series of VTE patients. To...
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