Article
Functional analyses of natural variation in Sp1 binding sites of a TATA-less promoter.
Journal of molecular evolution - 1 Dec 1999
Segal J A, Barnett J L, Crawford D L
Abstract excerpt
Within the lactate dehydrogenase-B (LdhB) proximal promoter is a region with multiple in vivo footprinted sites that resembles the binding site for the transcription factor SP1. Like many sequences that regulate transcription rate, these Sp1 binding sites are well conserved among species of the teleost fish Fundulus. The only exception is in the northern population of F. heteroclitus, where there are many changes...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
