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Article

Brain infection by neuroinvasive but avirulent murine oncornaviruses.

Journal of virology - 1 Jan 2000

Asković S, McAtee F J, Favara C, Portis J L

Abstract excerpt

The chimeric murine oncornavirus FrCas(E) causes a rapidly progressive noninflammatory spongiform encephalomyelopathy after neonatal inoculation. The virus was constructed by the introduction of pol-env sequences from the wild mouse virus CasBrE into the genome of a neuroinvasive but nonneurovirulent strain of Friend murine leukemia virus (FMuLV), FB29. Although the brain infection by FrCas(E) as well as that by...

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Identifiers

PMID: 10590136
DOI: 10.1128/jvi.74.1.465-473.2000
PMCID: PMC111558

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