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Article

Chemical intervention of influenza virus mRNA nuclear export

2 Apr 2020

Abstract excerpt

Influenza A viruses are human pathogens with limited therapeutic options. Therefore, it is crucial to devise strategies for the identification of new classes of antiviral medications. The influenza A virus genome is constituted of 8 RNA segments. Two of these viral RNAs are transcribed into mRNAs that are alternatively spliced. The M1 mRNA encodes the M1 protein but is also alternatively spliced to yield the M2...

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PMID: 32240278
DOI: 10.1371/journal.ppat.1008407

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