Article
Increased prevalence of VNTR III of the insulin gene in women with gestational diabetes mellitus (GDM).
Diabetes research and clinical practice - 1 May 2007
Litou Hariklia, Anastasiou Eleni, Thalassinou Louminitsa, Sarika Helen-Leda, Philippou George, Alevizaki Maria
Abstract excerpt
OBJECTIVE: The VNTR polymorphism in the promoter region of the insulin gene (INS-VNTR) affects transcription rate and has been associated with insulin resistance and DM2. Gestational diabetes mellitus (GDM) is a multifactorial disorder, where both impaired insulin secretion and action may be involved. The aim of the study was to examine the distribution of the INS-VNTRs in women with GDM and to investigate...
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