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Article

Identification of the Hb Lepore phenotype by HPLC.

Haematologica - 1 Dec 1999

Ropero P, González F A, Sánchez J, Anguita E, Asenjo S, Del Arco A, Murga M J, Ramos R, Fernández C, Villegas A

Abstract excerpt

BACKGROUND AND OBJECTIVE: Hb Lepore is a structurally abnormal hemoglobin in which the abnormal globin chain is a hybrid or fused globin chain (db). Three different Lepore hemoglobins have been identified, differing from each other in the point at which the db fusion occurs; Hb Lepore Hollandia (d22/b50), Hb Lepore Baltimore (d59/b86) and Hb Lepore Boston (d87/b116). In Spain only Hb Lepore Boston and Hb Lepore...

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PMID: 10586208

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