Article
Molecular and clinical analysis of haemoglobin Lepore in Campania, a region of Southern Italy.
Hematology (Amsterdam, Netherlands) - 1 Aug 2017
Ricchi Paolo, Ammirabile Massimiliano, Spasiano Anna, Costantini Silvia, Di Matola Tiziana, Cinque Patrizia, Saporito Caterina, Filosa Aldo, Pagano Leonilde
Abstract excerpt
OBJECTIVE: To date in Italy, there is paucity on data about the prevalence, clinical and haematological features of patients carrying the haemoglobin (Hb) Lepore variant in homozygous or in association with other haemoglobinopathies. METHODS: Here we report the results of a retrospective analysis on 33 patients from Campania, a region of Southern Italy, historically followed at 'UOSD Malattie Rare del Globulo...
Topics
- Adolescent
- Adult
- Alleles
- Biomarkers
- Blood Transfusion
- Child
- Child, Preschool
- Female
- Genetic Variation
- Hemoglobinopathies
- Hemoglobins, Abnormal
- Heterozygote
- Homozygote
- Humans