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Article

Hemoglobin Lepore Hollandia in India.

International journal of laboratory hematology - 1 Apr 2012

Nadkarni A, Italia K, Sawant P, Ghosh K, Colah R

Abstract excerpt

INTRODUCTION: Hb Lepore is a structurally abnormal hemoglobin in which the abnormal globin chain is a hybrid or fused δβ globin chain. In the heterozygous condition, Hb Lepore produces the phenotype of heterozygous β thalassemia with slightly raised HbF levels. METHOD: Using a combination of HPLC and DNA analysis, we have identified eight individuals with Hb Lepore Hollandia from three families including seven...

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PMID: 21895987
DOI: 10.1111/j.1751-553X.2011.01372.x

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