Article
Adhesion and invasion of a mutant Shigella flexneri to an eukaryotic cell line in absence of the 220-kb virulence plasmid.
FEMS microbiology letters - 15 Dec 1999
Guhathakurta B, Sasmal D, Ghosh A N, Kumar R, Saha P, Biswas D, Khetawat D, Datta A
Abstract excerpt
A Shigella flexneri strain, cured of the large 220-kb virulence plasmid, expresses adhering and invading ability in confluent monolayers of HeLa cells similar to its parent strain. Invasion by both the parent and the cured strains resulted in alteration of the monomeric actin (G) in the total actin pool of HeLa cells. Other indicators of invasive characteristics of virulent Shigella strains such as production of...
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