Shigella flexneri induces apoptosis in infected macrophages.

doi:10.1038/358167a0

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Article

Shigella flexneri induces apoptosis in infected macrophages.

Nature - 9 Jul 1992

Zychlinsky A, Prevost M C, Sansonetti P J

Abstract excerpt

The Gram-negative bacterial pathogen Shigella flexneri causes dysentery by invading the human colonic mucosa. Bacteria are phagocytosed by enterocytes, escape from the phagosome into the cytoplasm and spread to adjacent cells. After crossing the epithelium, Shigella reaches the lamina propria of...

Topics

Animals
Cell Death
Cell Line
Cell Nucleus
Cytochalasin D
Cytoplasm
DNA
Hemolysin Proteins
Kinetics
Macrophages
Mice
Microscopy, Electron
Mutation
Shigella flexneri

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