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Article

The B‐cell system of human mucosae and exocrine glands

1 Oct 1999

Abstract excerpt

The mucosae and exocrine glands harbour the largest activated B-cell system of the body, amounting to some 80-90% of all immunoglobulin (Ig)-producing cells. The major product of these immunocytes is polymeric (p)IgA (mainly dimers) with associated J chain. Both pIgA and pentameric IgM contain a binding site for the polymeric Ig receptor (pIgR), or secretory component (SC), which is a requirement for their active...

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PMID: 10582165
DOI: 10.1111/j.1600-065x.1999.tb01342.x

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