Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A selective screen reveals discrete functional domains in Drosophila Nanos.

Genetics - 1 Dec 1999

Arrizabalaga G, Lehmann R

Abstract excerpt

The Drosophila protein Nanos encodes an evolutionarily conserved protein with two zinc finger motifs. In the embryo, Nanos protein function is required for establishment of the anterior-posterior body pattern and for the migration of primordial germ cells. During oogenesis, Nanos protein is involved in the establishment and maintenance of germ-line stem cells and the differentiation of oocyte precursor cells. To...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Movement
Share to Drosophila
Share to Drosophila Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Insect Proteins

Share to Morphogenesis

Share to RNA-Binding Proteins

Share to Sequence Homology, Amino Acid

Share to Zinc Fingers

Source

Open in PubMed Open full text

Identifiers

PMID: 10581288
DOI: 10.1093/genetics/153.4.1825
PMCID: PMC1460875

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A selective screen reveals discrete functional domains in Drosophila Nanos.PMID 10581288Read ↗

A CCHC metal-binding domain in Nanos is essential for translational regulation.Semantic proximity Read ↗

Conserved role of nanos proteins in germ cell development.Semantic proximity Read ↗

Nanos and Pumilio have critical roles in the development and function of Drosophila germline stem cells.Semantic proximity Read ↗

Mutations of NANOS1, a human homologue of the Drosophila morphogen, are associated with a lack of germ cells in testes or severe oligo-astheno-teratozoospermia.Semantic proximity Read ↗

Highlighted article: "E(nos)/CG4699 is required for nanos function in the female germ line of Drosophila" by Yu, Song and Wharton.Semantic proximity Read ↗

PIE-1 is a bifunctional protein that regulates maternal and zygotic gene expression in the embryonic germ line of Caenorhabditis elegans.Semantic proximity Read ↗

Nanos downregulates maternal mRNAs in germline during Drosophila early embryogenesisSemantic proximity Read ↗

Wolbachia Protein TomO Targets nanos mRNA and Restores Germ Stem Cells in Drosophila Sex-lethal MutantsSemantic proximity Read ↗

E(nos)/CG4699 required for nanos function in the female germ line of Drosophila.Semantic proximity Read ↗

The Caenorhabditis elegans gene sem-4 controls neuronal and mesodermal cell development and encodes a zinc finger protein.Semantic proximity Read ↗

Specification of the germline by Nanos-dependent down-regulation of the somatic synMuvB transcription factor LIN-15BSemantic proximity Read ↗

Identification of mushroom body miniature, a zinc-finger protein implicated in brain development of Drosophila.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.