Nanos and Pumilio have critical roles in the development and function of Drosophila germline stem cells.

doi:10.1242/dev.125.4.679

Back to search

Article

Nanos and Pumilio have critical roles in the development and function of Drosophila germline stem cells.

Development (Cambridge, England) - 1 Feb 1998

Forbes A, Lehmann R

Abstract excerpt

The zinc-finger protein Nanos and the RNA-binding protein Pumilio act together to repress the translation of maternal hunchback RNA in the posterior of the Drosophila embryo, thereby allowing abdomen formation. nanos RNA is localized to the posterior pole during oogenesis and the posteriorly synt...

Topics

Animals
Cell Differentiation
Cell Movement
Drosophila
Drosophila Proteins
Female
Gene Expression Regulation, Developmental
Genes, Insect
Germ Cells
Insect Proteins
Male
Mutation
Phenotype
RNA-Binding Proteins
Stem Cells
Zygote

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.