Article
In vivo modification of porin activity conferring antibiotic resistance to Enterobacter aerogenes.
Biochemical and biophysical research communications - 9 Dec 1999
Chevalier J, Pagès J M, Malléa M
Abstract excerpt
Cephalosporins are widely used in chemotherapy of bacterial infections and resistance mechanisms seriously impair their antibacterial activity. Several resistant strains of Enterobacter aerogenes, a frequently isolated nosocomial pathogen, were analyzed. One isolate exhibited a strong modification of the porin antigenic pattern, especially with an immunological probe directed against an epitope located inside the...
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