Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Why are carbapenems active against Enterobacter cloacae resistant to third generation cephalosporins?

Scandinavian journal of infectious diseases. Supplementum - 1 Jan 1991

Pechère J C

Abstract excerpt

The broad antibacterial activity of carbapenems includes Gram-negative rods resistant to third generation cephalosporins. To increase the understanding of this improved activity, the factors involved in the efficacy of imipenem and ceftriaxone against Enterobacter cloacae have been examined. Resi...

Topics

Bacterial Outer Membrane Proteins
Bacterial Proteins
Carrier Proteins
Ceftriaxone
Cell Membrane Permeability
Drug Resistance, Microbial
Enterobacter cloacae
Hexosyltransferases
Imipenem
Muramoylpentapeptide Carboxypeptidase
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Penicillin-Binding Proteins

Peptidyl Transferases

Porins

beta-Lactamases

Source

Identifiers

PMID: 1658922

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1658922-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Why are carbapenems active against Enterobacter cloacae resistant to third generation cephalosporins?PMID 1658922Read ↗

The contribution of porins to enterobacterial drug resistance.Semantic proximity Read ↗

Imipenem- and meropenem-resistant mutants of Enterobacter cloacae and Proteus rettgeri lack porins.Semantic proximity Read ↗

Association of two resistance mechanisms in a clinical isolate of Enterobacter cloacae with high-level resistance to imipenemSemantic proximity Read ↗

An adaptive response of Enterobacter aerogenes to imipenem: regulation of porin balance in clinical isolates.Semantic proximity Read ↗

Consecutive mutations leading to the emergence in vivo of imipenem resistance in a clinical strain of Enterobacter aerogenes.Semantic proximity Read ↗

Activity of cefepime and other beta-lactam antibiotics against permeability mutants of Escherichia coli and Klebsiella pneumoniae.Semantic proximity Read ↗

Prevalence of outer membrane porin alteration in beta-lactam-antibiotic-resistant Enterobacter aerogenes.Semantic proximity Read ↗

Extension of resistance to cefepime and cefpirome associated to a six amino acid deletion in the H-10 helix of the cephalosporinase of an<i>Enterobacter cloacae</i>clinical isolateSemantic proximity Read ↗

In vivo modification of porin activity conferring antibiotic resistance to Enterobacter aerogenes.Semantic proximity Read ↗

Hydrolytic rate at low drug concentration as a limiting factor in resistance to newer cephalosporins.Semantic proximity Read ↗

Effect of cefoxitin and clindamycin on selection of derepressed mutants in Enterobacter cloacae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.