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Article

Developmental Seizure Susceptibility of Kv1.1 Potassium Channel Knockout Mice

1 Jan 1999

Abstract excerpt

Potassium channels play a critical role in limiting neuronal excitability. Mutations in certain voltage-gated potassium channels have been associated with hyperexcitable phenotypes in both humans and animals. However, only recently have mutations in potassium channel genes (i.e. KCNQ2 and KCNQ3) been discovered in a human epilepsy, benign familial neonatal convulsions. Recently, it has been reported that mice...

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PMID: 10575255
DOI: 10.1159/000017381

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Developmental Seizure Susceptibility of Kv1.1 Potassium Channel Knockout MicePMID 10575255Read ↗

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