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Article

Polymorphisms of the prion-related protein gene are strongly associated with cervids' susceptibility to chronic wasting disease.

The Veterinary record - 1 Feb 2022

Roh In-Soon, Kim Yong-Chan, Kim Hyo-Jin, Won Sae-Young, Jeong Min-Ju, Hwang Ji-Yong, Kang Hae-Eun, Sohn Hyun-Joo, Jeong Byung-Hoon

Abstract excerpt

BACKGROUND: Chronic wasting disease (CWD) is a cervid prion disease that is caused by abnormal prion protein (PrPSc ). Recent studies have reported that prion family genes showed a strong association with the susceptibility of several types of prion diseases. To date, an association study of the prion-related protein gene (PRNT) has not been performed in any type of cervid prion disease. METHODS: In the present...

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PMID: 34562285
DOI: 10.1002/vetr.940

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