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Article

The extent of genetic diversity of Epstein-Barr virus and its geographic and disease patterns: a need for reappraisal.

Virus research - 1 Aug 2009

Chang Cindy M, Yu Kelly J, Mbulaiteye Sam M, Hildesheim Allan, Bhatia Kishor

Abstract excerpt

Epstein-Barr virus (EBV) is a ubiquitous, gamma-1 lymphotrophic virus etiologically linked to nasopharyngeal carcinoma (NPC), endemic to Southern China, and Burkitt lymphoma (BL), endemic to equatorial Africa, both of which are rare elsewhere in the world. Why EBV is associated with different malignancies in different geographic regions remains puzzling and may be related to EBV genotypic variability through...

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Identifiers

PMID: 19596032
DOI: 10.1016/j.virusres.2009.07.005
PMCID: PMC2731007

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