Article
The HLA complex in Goodpasture's disease: a model for analyzing susceptibility to autoimmunity.
Kidney international - 1 Nov 1999
Phelps R G, Rees A J
Abstract excerpt
Human lymphocyte antigen (HLA) associations are recognized for many autoimmune diseases, but the mechanisms are not clear. Goodpasture's disease provides a unique opportunity to investigate possible mechanisms because strong HLA associations are known, the autoantigen is well defined, and major antigen-derived peptides presented bound to HLA molecules have been identified. Therefore, it may be possible to...
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