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Article

Physiological role of tumor necrosis factor alpha in traumatic muscle injury.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Oct 2002

Warren Gordon L, Hulderman Tracy, Jensen Nancy, McKinstry Michael, Mishra Michael, Luster Michael I, Simeonova Petia P

Abstract excerpt

degenerative and regenerative roles of tumor necrosis factor alpha (TNF-alpha), a pro-inflammatory cytokine with pleiotropic functions, were investigated by using TNF receptor 1 and 2 double knockout (TNFR-DKO) and TNF-alpha antibody neutralized mice following traumatic freeze injury to the tibialis anterior muscle. In wild-type control mice, TNF-alpha mRNA transcripts and protein increased following injury and...

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Source

Identifiers

PMID: 12207010
DOI: 10.1096/fj.02-0187fje

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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