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Article

Molecular analysis of chromosomal breakpoints in three examples of chromosomal translocation involving the TEL gene.

Leukemia - 1 Nov 1999

Romana S, Poirel H, Della Valle V, Mauchauffé M, Busson-Le Coniat M, Berger R, Bernard O A

Abstract excerpt

The TEL gene is involved in several chromosomal abnormalities of human hematopoietic malignancies. The chromosome 12 breakpoints frequently lie within the fifth intron of the gene, particularly in the most frequent translocation involving TEL, the t(12;21)(p13;q22). In order to search for a peculiar mechanism involved in the genesis of these translocations, we have established the sequence of two t(12;21) and a...

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PMID: 10557049
DOI: 10.1038/sj.leu.2401564

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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