Article
Dinucleotide repeat polymorphisms within the Flt-1 gene in minimal change nephropathy.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Oct 1999
Parry R G, Gillespie K M, Clark A G, Mathieson P W
Abstract excerpt
Dysregulation of Flt-1, a major receptor for vascular permeability factor (VPF), may provide a mechanism for the development of proteinuria in minimal change nephropathy (MCN). The gene for Flt-1 has a polymorphic dinucleotide repeat. We have demonstrated an 88% predominance of one allele and an 80% rate of homozygosity for this polymorphism with no association with MCN.
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