Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dinucleotide repeat polymorphism in Fms-like tyrosine kinase-1 (Flt-1) gene is not associated with preeclampsia.

BMC medical genetics - 17 Jul 2008

Kim Shin-Young, Lim Ji-Hyae, Yang Jae-Hyug, Kim Moon-Young, Han Jung-Yeol, Ahn Hyun-Kyong, Choi Jun-Seek, Park So-Yeon, Kim Mi-Jin, Ryu Hyun-Mee

Abstract excerpt

BACKGROUND: Preeclampsia is a major cause of maternal and perinatal mortality and morbidity. The etiology of preeclampsia remains unclear. Recently, it was shown that misregulation of fms-like tyrosine kinase-1 (Flt-1) in the peripheral blood mononuclear cells of pregnant women results in over-expression of the soluble splice variant of Flt-1, sFlt-1, producing an additional (extra-placental) source of sFlt-1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chi-Square Distribution
Share to Dinucleotide Repeats

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Odds Ratio

Share to Pre-Eclampsia

Share to Pregnancy

Share to Sequence Analysis, DNA

Share to Vascular Endothelial Growth Factor Receptor-1

Source

Open in PubMed Open full text

Identifiers

PMID: 18631405
DOI: 10.1186/1471-2350-9-68
PMCID: PMC2496902

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dinucleotide repeat polymorphism in Fms-like tyrosine kinase-1 (Flt-1) gene is not associated with preeclampsia.PMID 18631405Read ↗

Both Fetal and Maternal Genotypes Affect Preeclampsia Pathogenesis in Iranian Patients.Semantic proximity Read ↗

Genetic predisposition to preeclampsia is conferred by fetal DNA variants near FLT1, a gene involved in the regulation of angiogenesis.Semantic proximity Read ↗

Protective Low-Frequency Variants for Preeclampsia in the Fms Related Tyrosine Kinase 1 Gene in the Finnish Population.Semantic proximity Read ↗

No association between polymorphisms/haplotypes of the vascular endothelial growth factor gene and preeclampsia.Semantic proximity Read ↗

Variants in the fetal genome near FLT1 are associated with risk of preeclampsia.Semantic proximity Read ↗

Associations between AGT, MTHFR, and VEGF gene polymorphisms and preeclampsia in the Chinese population.Semantic proximity Read ↗

Genetic Variants Associated With Preeclampsia and Maternal Serum sFLT1 Levels.Semantic proximity Read ↗

Preeclampsia association of placental nucleotide variations in eNOS, VEGFA, and FLT-1 genes in Latin American pregnant women.Semantic proximity Read ↗

Vascular endothelial growth factor +936C/T and -634G/C polymorphisms exhibited significantly different allelic distributions and no associations with the risk of preeclampsia, gestational hypertension or gestational diabetes mellitus in the Xinjiang Uygur Autonomous Region of ChinaSemantic proximity Read ↗

No association of the genetic polymorphisms of endothelial nitric oxide synthase, dimethylarginine dimethylaminohydrolase, and vascular endothelial growth factor with preeclampsia in Korean populations.Semantic proximity Read ↗

Differential placental methylation and expression of VEGF, FLT- 1 and KDR genes in human term and preterm preeclampsiaSemantic proximity Read ↗

Fetal-Not Maternal-APOL1 Genotype Associated with Risk for Preeclampsia in Those with African Ancestry.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.