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Article

Analysis of SCAMP1 function in secretory vesicle exocytosis by means of gene targeting in mice.

The Journal of biological chemistry - 12 Nov 1999

Fernández-Chacón R, Alvarez de Toledo G, Hammer R E, Südhof T C

Abstract excerpt

Secretory carrier membrane proteins (SCAMPs) comprise a family of ubiquitous membrane proteins of transport vesicles with no known function. Their universal presence in all cells suggests a fundamental role in membrane traffic. SCAMPs are particularly highly expressed in organelles that undergo regulated exocytosis, such as synaptic vesicles and mast cell granules. Of the three currently known SCAMPs, SCAMP1 is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10551807
DOI: 10.1074/jbc.274.46.32551

Genes

SCAMP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Analysis of SCAMP1 function in secretory vesicle exocytosis by means of gene targeting in mice.PMID 10551807Read ↗

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Molecular analysis of SNAP-25 function in exocytosis.Semantic proximity Read ↗

TPC1 deficiency or blockade augments systemic anaphylaxis and mast cell activity.Semantic proximity Read ↗

Synaptotagmin-1 utilizes membrane bending and SNARE binding to drive fusion pore expansion.Semantic proximity Read ↗

Synaptotagmin oligomerization is essential for calcium control of regulated exocytosis.Semantic proximity Read ↗

SCAMP2 interacts with Arf6 and phospholipase D1 and links their function to exocytotic fusion pore formation in PC12 cells.Semantic proximity Read ↗

The functions of Munc18-1 in regulated exocytosis.Semantic proximity Read ↗

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