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Article

Telomerase activity in human intestine

1 Sept 1996

Abstract excerpt

In human somatic cells without the activity of telomerase, the ends of chromosomes consisting of the telomeric repeats TTAGGG progressively erode with each cell division. In germline and immortal cells telomerase activity maintains telomere length and thus compensates for the 'end-replication problem'. Progressive telomere shortening and reactivation of telomerase activity have been considered to be one of the...

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Share to Digestive system and related health
Share to Telomeres, Telomerase, and Senescence
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Identifiers

PMID: 21541534
DOI: 10.3892/ijo.9.3.453

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Telomerase activity in human intestinePMID 21541534Read ↗

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GERD is associated with shortened telomeres in the squamous epithelium of the distal esophagusSemantic proximity Read ↗

Telomerase inhibition by an siRNA directed against hTERT leads to telomere attrition in HT29 cellsSemantic proximity Read ↗

Developmental regulation of telomerase activity in human fetal tissues during gestationSemantic proximity Read ↗

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