Zoning of mucosal phenotype, dysplasia, and telomerase activity measured by telomerase repeat assay protocol in Barrett's esophagus.

Article

Zoning of mucosal phenotype, dysplasia, and telomerase activity measured by telomerase repeat assay protocol in Barrett's esophagus.

Neoplasia (New York, N.Y.) - 1 Jan 2000

Going James J, Fletcher-Monaghan Aileen J, Neilson Lisa, Wisman Bea A, van der Zee Ate, Stuart Robert C, Keith W Nicol

Abstract excerpt

Glandular dysplasia in Barrett's esophagus may regress spontaneously but can also progress to cancer. The human telomerase RNA template and the human telomerase reverse transcriptase enzyme which do not, of themselves, correlate strongly with telomerase activity, are too often overexpressed in Ba...

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